#1016 Pathophysiology: The Immune System (15 Credits/Hours)

(15 Credits/Hours)

Launch Date: August 5, 2025
Expires: August 31, 2027

Course Overview

This comprehensive course explores the complex mechanisms of immune system dysfunction and disease. Students will examine how disruptions in normal immune function lead to various pathological conditions, from autoimmune disorders to immunodeficiencies. The course integrates molecular, cellular, and systemic perspectives to understand immune-mediated diseases and their clinical manifestations.

Table of Contents

1. Introduction to Immune System Pathophysiology
2. Dysregulation of Innate Immunity
3. Adaptive Immune System Dysfunction
4. Primary Immunodeficiency Disorders
5. Secondary Immunodeficiency Syndromes
6. Autoimmune Disease Mechanisms
7. Systemic Autoimmune Disorders
8. Organ-Specific Autoimmune Diseases
9. Hypersensitivity Reactions and Allergic Diseases
10. Chronic Inflammatory Disorders
11. Immune System and Cancer Pathophysiology
12. Transplant Rejection and Graft-versus-Host Disease
13. Infectious Disease and Immune System Failure
14. Immunosenescence and Age-Related Immune Dysfunction

 Learning Objectives
Upon completion of this course, you will be able to:

• Analyze the pathophysiological mechanisms underlying immune system disorders
• Evaluate the molecular and cellular basis of immune dysfunction
• Distinguish between different types of immune-mediated pathologies
• Assess the clinical manifestations of immune system diseases
• Explain the relationship between immune system failure and disease susceptibility
• Apply knowledge of immune pathophysiology to therapeutic interventions
• Integrate immune system pathology with other body systems
• Critically analyze current research in immune system pathophysiology